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Varenicline Stop Smoking Pill
A Pfizer drug shown to help more than one in five smokers stop smoking received federal approval on Thursday, adding another option to the limited pool of effective stop-smoking prescription medicines.
Varenicline is only the second nicotine-free smoking cessation drug to gain FDA approval. Pfizer Inc. plans to market the twice-daily tablet as Chantix stop smoking pill.
Quitting, as any smoker will tell you, isn't easy. Fewer than one in 20 smokers can do so without help, Schroeder said. With help, whether it's a drug, counseling or both, the success rate rises at most to roughly one in five, he added.
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"It's a shield and at the same time, it stabilizes you and prevents you from having the lows, which lead to craving and withdrawal, but at the same time, it shields you from the highs," said Coe, a former 2 1/2 pack-a-day smoker who quit smoking a first time cold turkey and then a second time with the help of nicotine gum.
And at least two vaccines are being developed that could block nicotine from ever reaching the brain. The FDA does not recommend that Chantix be used with other smoking-cessation products. Its most common side effect is nausea. To err is human, to forgive is divine. So we would indeed deem you to be divine if you forgive us for any misunderstandings that may arise in this article on overcome nicotine addiction.
The approved course of Chantix pill treatment is 12 weeks, a period that can be doubled in patients who successfully stop to increase the likelihood they will remain smoke-free, the Food and Drug Administration said.
Both the FDA and European regulators recently shot down attempts by Sanofi-Aventis to gain approval for rimonabant, or Accomplia, as a stop-smoking aid. Both have recommended that the drug, which blocks the same pleasure centers in the body activated when pot smokers get the munchies, be approved for weight loss.
Other clinical trials show the drug's effect is more pronounced in the short-term: 44 percent of patients quit smoking following a 12-week course of treatment with Chantix, compared to the 30 percent of Zyban patients who quit, according to Pfizer. However, smoking cessation experts said the longer-term data are more applicable, given the difficulty of quitting the habit for good.
One in five American adults, or nearly 45 million people, smoke. An estimated 32 million of those smokers would like to quit, according to the Centers for Disease Control and Prevention. Smoking kills nearly 440,000 Americans a year. We have used a mixture of seriousness and jokes in this composition on overcome nicotine addiction. This is to liven the mood when reading about overcome nicotine addiction.
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"My bet is that it will work as well as they do and, from the look of things, a little bit better," he said. Varenicline latches on to the same receptors in the brain that nicotine binds to when inhaled in cigarette smoke, an action that leads to the release of dopamine in the pleasure centers of the brain. Taking the drug blocks any inhaled nicotine from reinforcing that effect. Interesting is what we had aimed to make this article on overcome nicotine addiction. It is up to you to decide if we have succeeded in our mission!
"Tobacco use, particularly cigarette smoking, is the single most preventable cause of death in the United States and is responsible for a growing list of cancers, as well as chronic diseases including those of the lung and heart," said Dr. Scott Gottlieb, the FDA's Deputy Commissioner for Medical and Scientific Affairs.
Varenicline works in two ways, by cutting the pleasure of smoking and reducing the withdrawal symptoms that lead smokers to light up cigaret again. Most other stop-smoking pills are various nicotine-replacement therapies, sold by prescription and over the counter in gum, patch, lozenge, nasal spray or inhaler form. In 1997, the FDA approved bupropion, an antidepressant already sold as Wellbutrin but rebranded it as Zyban, an anti-smoking drug. Time and tide waits for no man. So once we got an idea for writing on overcome nicotine addiction, we decided not to waste time, but to get down to writing about it immediately!
The drug also slows the release of dopamine, which cuts the craving to smoke that occurs when nicotine's effect wears off, said Pfizer research chemist Jotham Coe, who invented the drug.
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Smoking has an addictive effect, due to its high nicotine content, and has become a hard habit to break for most people. One's health, as well as those surrounding the smoker, is primarily at stake, and is the major cause of disorders such as lung cancer and heart attack.
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